Differin Acne Spot Treatment carton with 10% benzoyl peroxide, 1 oz

Drug facts show on back of Differin Acne Spot Treatment carton with 10% benzoyl peroxide, 1 oz

Before-and-after cheek photos show visibly reduced acne after one day of Differin Acne Spot Treatment use, highlighted by dashed circles; blue text says “Real people, real results,” with a small results-may-vary disclaimer.

Skincare advertisement for Differin 10% benzoyl peroxide acne spot treatment, with a smiling woman applying cream to her cheek. Text says it helps unclog pores and kill acne-causing bacteria. The bright blue design feels upbeat and reassuring.

Advertisement for Differin Acne Spot four-in-one facial acne treatment, showing cream being applied and a finger touching a blemish; claims it reduces acne and clears clogged pores.

Blue Differin infographic featuring white skincare cream droplets and ingredient labels: benzoyl peroxide kills acne bacteria, acrylates copolymer removes excess oil, and glycerin smooths and softens skin.

how-to-use graphic:
Differin 10% benzoyl peroxide application guide showing cleansing, a thin layer and gradual increases in use.

Differin Acne Spot Treatment UK | 28g

£24.99 - £24.99

£24.99

£24.99 - £24.99

£24.99

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Differin Acne Spot Treatment · Original US 1 oz (28 g) tube

Target the Spot.10% Benzoyl Peroxide.

A leave-on acne treatment with 10% benzoyl peroxide to target acne-causing bacteria and blemishes. Formulated with glycerin, in a compact 28 g tube. Start carefully and follow the sensitivity-test instructions.

10% benzoyl peroxideLeave-on treatment1 oz (28 g)

A closer look at the treatment

Focused Acne Care.
A Formula Worth Understanding.

Differin Acne Spot Treatment is a US-market topical acne treatment supplied in a tube with a net weight of 1 oz (28 g). Its active ingredient is benzoyl peroxide at 10%. The tube is designed for applying a thin layer to affected skin as directed, with a sensitivity test before a new user starts regular application.

Benzoyl peroxide targets acne-causing bacteria. Differin describes this formula as helping to clear blemishes and prevent future breakouts, including blackheads and whiteheads. It is a leave-on treatment: its role in a routine differs from a cleanser that is washed away. Check the product name and active ingredient when choosing between products with similar blue Differin packaging.

The carton uses the wording maximum strength. This refers to the US benzoyl peroxide spot-treatment concentration; it is not a reason to apply a thicker layer or begin at the highest frequency. Skin tolerance matters. The Drug Facts specifically excludes very sensitive skin and sensitivity to benzoyl peroxide, and introduces the product with a three-day test.

The acne-treatment ingredient10%Benzoyl
PeroxideLeave-on acne treatment

What the percentage means

A Defined Strength.
A Thin-Layer Application.

The 10% figure identifies the benzoyl peroxide concentration in the formula. On the US label, benzoyl peroxide is the active ingredient and acne treatment is its purpose. The amount you apply is still a thin layer, following the directions for the affected area.

A 10% leave-on product and a 10% wash have different application instructions, even when they share the same ingredient percentage. Use this tube according to its own Drug Facts. In particular, keep the sensitivity test, gradual starting frequency and sunscreen guidance as part of your routine.

Supporting ingredient

Formulated with Glycerin.

Glycerin is included as a moisturising ingredient. Differin describes it as helping to minimise dryness while benzoyl peroxide treats acne. Dryness and peeling can still occur, so its inclusion does not remove the need to monitor your skin or adjust use as directed.

Understand the name

Benzoyl Peroxide, Not Adapalene.

This spot treatment contains benzoyl peroxide. Differin Gel contains adapalene, a retinoid, and is a different product. Do not transfer its directions or age guidance to this tube simply because both carry the Differin name.

Pack size

28 g of Product.

The carton states net weight 1 oz (28 g). This describes the contents of the tube, rather than a volume in millilitres or a fixed number of applications. How long a tube lasts depends on the area treated and the frequency used within the label directions.

Before regular application

Start with the Test.Then Build Gradually.

A new user should begin with the sensitivity test. Move on to regular application only if that test causes no discomfort.

Sensitivity test · first three daysSmall Areas.
Sparing Amount.

Apply sparingly to one or two small affected areas during the first three days. If no discomfort occurs, follow the regular directions below.

01 · prepare

Clean the Skin.

Clean the skin thoroughly before applying. Cover the entire affected area with a thin layer, following the Drug Facts on the tube or carton. Avoid the eyes, lips and mouth.

02 · begin

Start Once Daily.

Begin with one application each day because excessive drying can occur. Increase gradually to two or three applications daily only if needed or as directed by a doctor.

03 · monitor

Respond to Your Skin.

If bothersome dryness or peeling develops, reduce use to once daily or every other day. Severe irritation means stop using the treatment and ask a doctor.

When going outdoors, apply sunscreen after this treatment and avoid unnecessary sun exposure. If irritation or sensitivity develops when using the treatment and sunscreen, the label instructs you to stop both products and ask a doctor. Keep those steps alongside the application frequency rather than treating sun protection as an optional finishing detail.

The formula on the US label

One Active Ingredient.
The Full Supporting Formula.

Differin Acne Spot Treatment — US Drug Facts
Active ingredient	Strength
Benzoyl peroxide	10%

Inactive Ingredients.

Acrylates copolymer, carbomer, diethylhexyl sodium sulfosuccinate, disodium EDTA, glycerin, poloxamer 182, propylene glycol, silica, sodium hydroxide, water.

Ingredient names follow the reviewed US Drug Facts and manufacturer list. Check the complete label on the product supplied, particularly if you have sensitivities. These details identify this benzoyl peroxide treatment, rather than another product in the Differin range.

Results in context

Give the Claim Its Context.

Differin says the formula can visibly reduce acne size and redness after one day. Individual results vary, and that claim does not mean every blemish will disappear overnight. Follow the gradual-use instructions rather than increasing the amount in pursuit of a faster result.

Everyday practicalities

Think About Fabrics.

Benzoyl peroxide can bleach hair and dyed fabrics. Take care around towels, pillowcases and clothing, and avoid contact with hair. This practical warning applies to the leave-on treatment even when you are using only a thin layer.

Read before use

Safety &
Important Information.

A 10% benzoyl peroxide treatment for external use. Read the complete Drug Facts on your pack before starting.

Very Sensitive Skin? Do Not Use.

The US label says do not use if you have very sensitive skin or are sensitive to benzoyl peroxide. A new user must follow the three-day sensitivity-test directions.

Watch for Irritation.

Redness, burning, itching, peeling and swelling can occur. Irritation may improve with less frequent use or a lower concentration. If irritation becomes severe, stop use and ask a doctor.

Other Acne Medicines.

Using another topical acne medicine at the same time increases the risk of dryness and irritation. If irritation occurs, use only one topical acne medicine at a time. Ask your prescriber before changing a prescribed routine.

Sun Exposure.

Avoid unnecessary sun exposure and use sunscreen. Apply sunscreen after this treatment when going outside. If irritation or sensitivity develops, stop using both products and ask a doctor.

External Use Only.

Avoid contact with the eyes, lips and mouth. This is a skin treatment and must not be swallowed.

Hair & Dyed Fabrics.

Keep the treatment away from hair and dyed fabrics, which can be bleached by benzoyl peroxide.

Children & Swallowing.

Keep out of reach of children. If swallowed, obtain medical help immediately. The reviewed US Drug Facts does not state a minimum age; ask a pharmacist or doctor before using it for a child.

Information checked against the manufacturer and official US Drug Facts, 26 October 2026. Follow the complete directions, precautions and any storage guidance on the pack supplied. Ask a pharmacist or doctor about individual suitability.

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We source US stock through authorised US pharmacies or wholesale distributors, with the product identity and pack details made clear.

Know the exact product

Clear Ingredient Information.

This listing identifies the 10% benzoyl peroxide spot treatment in the US 1 oz (28 g) tube, with its own sensitivity-test instructions and important precautions.

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Differin 10% spot treatment · your questions answered

Clear Answers.For UK Buyers.

The active ingredient, starting routine, sensitivity test and key precautions, explained for this exact treatment.

Can you buy Differin 10% Benzoyl Peroxide Spot Treatment in the UK?

Yes, you can buy Differin 10% Benzoyl Peroxide Spot Treatment in the UK through specialist importers like Kingdom States. This listing is for the US 1 oz (28 g) tube. Check the current product availability above and read the complete directions and warnings before use.

What does this Differin spot treatment contain?

The active ingredient is benzoyl peroxide 10%, with acne treatment stated as its purpose on the US Drug Facts. The formula also includes glycerin. Differin describes benzoyl peroxide as targeting acne-causing bacteria to help clear blemishes.

Is this the same as Differin Adapalene Gel?

No. This spot treatment contains 10% benzoyl peroxide. Differin Gel contains adapalene, a retinoid, and is a different product. Follow the directions and precautions for the exact tube you are using; do not transfer the Gel's instructions to this spot treatment.

Do you rinse off Differin 10% Benzoyl Peroxide Spot Treatment?

This is a leave-on acne treatment. After the new-user sensitivity test, the label directs a thin layer over the affected area. It has different instructions from a rinse-off benzoyl peroxide cleanser.

How should a new user do the sensitivity test?

Apply the product sparingly to one or two small affected areas during the first three days. If no discomfort occurs, follow the regular application directions. The test does not override the warning against use on very sensitive skin or by anyone sensitive to benzoyl peroxide.

How often should you apply this spot treatment?

After the sensitivity test causes no discomfort, begin with one application daily. Increase gradually to two or three times daily only if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce use to once a day or every other day. Stop and ask a doctor if irritation becomes severe.

Can you use this on very sensitive skin?

No. The US Drug Facts says not to use the product if you have very sensitive skin or are sensitive to benzoyl peroxide. Glycerin in the formula does not remove this warning or guarantee irritation-free use.

Can you use other acne medicines at the same time?

Using another topical acne medicine at the same time increases the likelihood of skin irritation and dryness. If irritation occurs, the label says to use only one topical acne medicine at a time. Ask your prescriber before changing a prescribed acne routine.

Should you apply sunscreen with this treatment?

Avoid unnecessary sun exposure and use sunscreen. When going outside, apply sunscreen after this treatment. If irritation or sensitivity develops, the label instructs you to stop both products and ask a doctor.

Can benzoyl peroxide bleach towels or clothing?

Yes. The label warns that the product may bleach hair and dyed fabrics. Avoid contact with hair, towels, pillowcases and clothing that could be affected.

What is the minimum age for this product?

The reviewed US Drug Facts does not state a minimum age. Ask a pharmacist or doctor before using this 10% benzoyl peroxide treatment for a child, and keep it out of children's reach. Do not assume the age guidance for Differin Adapalene Gel applies to this product.

What size is the Differin spot treatment tube?

The US carton states a net weight of 1 oz (28 g), supplied in one tube. This is a weight measurement, rather than 1 fluid ounce or 30 ml. The pack does not establish a fixed number of applications or days of supply.

Answers checked against the manufacturer and official US Drug Facts, 26 October 2026. Read the Safety & Important Information above.

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