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Zymox Plus Advanced Formula 1% Hydrocortisone Otic Dog & Cat Ear Solution, 1.25 oz

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Zymox Plus Advanced Formula 1% Hydrocortisone Otic Dog & Cat Ear Solution

ZYMOX Advanced Formula Otic Plus cat and dog ear cleaner provides relief from persistent, recurring ear irritation or infection. Combined with veterinarian-strength 1% Hydrocortisone, Otic Plus helps calm itchy ears.

We’ve also added a biofilm-reducing complex to our advanced formula pet ear cleaner to help relieve stubborn ear infection-causing microorganisms that form resistant and hard-to-penetrate biofilms. This addition makes the Otic Plus formulation ideal for addressing recurrent ear infections and stubborn ear issues.

ZYMOX Otic Plus ear cleanser immediately begins working to clean your pet’s ears and dissolve debris that could be causing irritation. Our one-step process makes caring for your pet’s ears easy. Simply apply generously to uncleaned ears, filling the ear canal. Then, gently massage underneath the ear to allow the solution to work its way down to begin clearing away buildup.

ZYMOX Otic Plus provides simple, effective relief.

Recurrent ear infections and itchy, irritated ears can lead to a distressed pet and repeat visits to your veterinarian. They often mean repeat courses of antibiotics, too, which can lead to problems with resistant bugs that don’t respond to conventional antibiotic treatment.


The advanced technology of our patented LP3 Enzyme System is at the center of all ZYMOX products. These enzymes are found naturally in milk and are 100% safe. Each enzyme has unique properties; when combined, they pack a powerful antimicrobial punch. They work together to inhibit, split and destroy offending bacteria, fungi and even some viruses, making the combination antibacterial as well as antifungal.

Persistent, resistant microorganisms, such as pseudomonas and staph, often form hard-to-penetrate biofilms that make these microorganisms difficult to clear. The biofilm-reducing complex in Advanced Formula Otic PLUS targets these biofilms to help relieve irritating, painful symptoms.

ZYMOX Advanced Formula Otic Plus includes 1% Hydrocortisone for relief from itching and inflammation.

ZYMOX Otic Advanced Enzymatic ear cleaner is also available without Hydrocortisone (identified by a yellow product label) for antibiotic-sensitive animals, rodents, sensitive exotics, pets sensitive to Hydrocortisone and pets that are pregnant or lactating.


ZYMOX Otic Plus ear cleaner is an all-in-one solution for infections caused by bacteria, fungi and yeast.

Antibiotic-free, there’s no chance of microbes becoming resistant to our formula.

The LP3 Enzyme System reacts with biological materials within the ears to form its antimicrobial properties, working effectively without harming healthy cells

Simple To Use

Apply once a day to clean and soothe in one easy step with a simple daily dose.

There’s no need to cause fear or upset in your pet, as painful pre-cleaning is unnecessary.

In fact, pre-cleaning and cleaning while using Otic Plus disrupts the biological system and can negatively affect results.

Our unique formula won't cause irritation to your pet's ears or skin and is safe if your pet licks at the application site.



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